Endocrine Abstracts

Background: Hashimoto’s thyroiditis and Grave’s disease are the common autoimmune diseases of thyroid gland across all age groups. Some patients with autoimmune hyperthyroidism can become hypothyroid however it is rare for patients with hypothyroidism to develop Grave’s disease. Although some cases have been reported in adults, this phenomenon is very rare in the paediatric age group. Case: 13 year old Caucasian girl who was diagnosed with...

Background: Germline mutations in the Phosphatase and Tensin Homolog Hamartoma tumour (PTEN) gene are associated with a number of conditions, collectively known as PTEN hamartoma tumour syndromes (PHTS). Individuals with PHTS are at increased risk of a number of cancers primarily in adulthood including differentiated thyroid carcinoma (DTC) with an estimated lifetime risk of DTC of up to 38%. International guidance recommends screening commencing from 17 years while the 2017-U...

Introduction: Artificial pancreas systems (APS) have improved glycaemic control in adult and paediatric patients in clinical trials as part of routine clinical careAim and objectives: To evaluate the effectiveness of artificial pancreas system in routine clinical care on glycaemic control over a period of three to six months. Changes in glycated haemoglobin (HbA1c), time in range (TIR, 3.9-10 mmol/l) and time below range (TBR, <3.9 mmol/l) were asses...